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Clinical


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Clinical


Clinical Practice and Training

 

Assistant professor of Anesthesiology and pediatrics, 2014 - Present

Duke University Hospital, Durham, NC

 

Fellow in Pediatric Anesthesiology, 2013 - 2014

board certified (ABA), pediatric anesthesiology, September 2014

Texas Children's Hospital, Houston, TX

 

Resident in Anesthesiology, 2009 - 2013

board certified (ABA), anesthesiology,        April 2014

University of Washington Medical Center, Seattle, WA

Harborview Medical Center,
Seattle, WA

Seattle Children's Hospital,
Seattle, WA

Veteran Affairs Puget Sound Health Care System, Seattle, WA

 

Nathaniel Greene has been practicing clinical anesthesiology since the start of his residency in 2009.

He has always been interested in making the perioperative experience safer and less traumatic for all of his patients, especially children.

His practice and training has taken him to many different places across the country to learn from a large number of top experts from around the United States. He has been able to "pick and choose" from a plethora of styles and techniques offered to him to provide what he believes to be the safest and least traumatic methods of providing high quality care to children requiring anesthesia.

He has continued to refine his practice as an attending physician to be able to integrate the latest technological advances available to provide the highest quality care possible.

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Research


Research


Research

 

Peer-Reviewed Publications

Variation in Adult Traumatic Brain Injury Outcomes in the United States.

Greene NH, Kernic MA, Vavilala MS, Rivara FP.

J Head Trauma Rehabil. 2017 Apr 18. [ePub ahead of print]

Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heart surgery.

Tew S, Fontes ML, Greene NH, Kertai MD, Ofori-Amanfo G, Jaquiss RD, Lodge AJ, Ames WA, Homi HM, Machovec KA, Jooste EH

pediatric anesthesia, 2017 Mar;27(3):305-313.

Complete Obstruction of Endotracheal Tube in an Infant with a Retropharyngeal and Anterior Mediastinal Abscess

Thapa Db, udani ag, greene nh

case reports in pediatrics, january 2017, 1848945.

Airway Management in a Patient with Wolf-Hirschhorn Syndrome.

Gamble jf, kurian dj, udani ag, greene nh

case reports in pediatrics, July 2016, 7070125.

Increased Pediatric Sub-specialization is Associated with Decreased Surgical Complication Rates for Inpatient Pediatric Urology Procedures

tejwani r, wang hs, young bj, greene nh, wolf s, wiener js, routh jc

Journal of Pediatric Urology, june 2016, S1477-5131(16)30126-7.

Midazolam for anxiolysis and postoperative nausea and vomiting prophylaxis: can we kill two birds with one stone?

greene nh, Habib as

Anesthesia & Analgesia, March 2016, 122(3):590-2.

Implementation of Real Time Feedback to Anesthesiology Trainees in the Prevention of Postoperative Nausea and Vomiting

greene nh, norstedt pa, nair bg, souter kj

journal of education in perioperative medicine, 2015, Volume XvII - Issue III.

Validation of ICDPIC Software Injury Severity Scores Using a Large Regional Trauma Registry

greene nh, kernic ma, vavilala ms, rivara fp

injury prevention, october 2015, 21(5):325-30.

Measurements of Epidural Space Depth Using Preexisting CT Scans Correlate with Loss of Resistance Depth during Thoracic Epidural Catheter Placement

Greene nh, cobb bg, linnau kf, kent cd

Anesthesiology research and practice, 2015, 545902.

Variation in Inpatient Rehabilitation Utilization After Hospitalization for Burn Injury in the United States

Greene nh, Pham TN, Esselman PC, Rivara FP

Journal of burn care and research, november-december 2015, 36(6):613-8.

Perioperative Management of Carotid Endarterectomy: A Survey of Clinicians' Backgrounds and Practices

greene nh, Minhaj mm, zaky af, rozet i

journal of cardiothoracic and vascular anesthesia, august 2014, 28(4):1002-5.

Variation in Pediatric Traumatic Brain Injury Outcomes in the United States

Greene nh, Kernic Ma, vavilala Ms, Rivara FP

Archives of Physical medicine and rehabilitation, June 2014, 95(6):1148-1155.

Spinal anesthesia for Cesarean delivery in a woman with Neuromyelitis Optica

greene N, dinges e, ciliberto c, sedensky m, landau r

A&A Case reports, may 2014, 2(9):108-110.

Modern Understanding of Cerebral Perfusion and Autoregulation

Greene nh, Lee la

advances in anesthesia, 2012, 30:97-129.

Vascular Access, Fluid Management, and Blood Transfusion in Pediatric Trauma

Greene nh, Bhananker s, ramaiah r

international journal of critical illness and injury science, september-december 2012, 2(3):135-42.

Measures of Executive Function and Depression Identify Patients at Risk for Postoperative Delirium

Greene NH, Attix DK, weldon bc, smith pj, mcdonagh dl, Monk tg

anesthesiology, april 2009; 110(4):788-95.

Executive Function and Depression as Independent Risk Factors for Postoperative Delirium

Smith pj, attix dk, weldon bc, Greene nh, Monk TG

Anesthesiology, April 2009; 110(4):781-7.

 

Book Chapters

The Pediatric Perioperative Cardiac Arrest (POCA) Registry

Greene nh, Bhananker SM, posner kl, domino kb

Pediatric and congenital cardiac care - volume 2: Quality improvement and patient safety, edited by Paul R. Barach, Jeffrey p. Jacobs, peter c. LAussen, and steven e. lipshultz; springer, december 5th, 2014.

Pediatric Trauma and Burn Injury

Greene NH, Estrada C

ondensed review of PEDIATRIC anesthesiology, 2nd edition, edited by christopher estrada, stephen stayer, david mann, nicholas carling, nihar patel, and paul hopkins, 2014.

Statistics and Diagnostics

greene nh,Easley RB

CONDENSED REVIEW OF PEDIATRIC ANESTHESIOLOGY, 2ND EDITION, EDITED BY CHRISTOPHER ESTRADA, STEPHEN STAYER, DAVID MANN, NICHOLAS CARLING, NIHAR PATEL, AND PAUL HOPKINS, 2014.

Clinical Studies and Assessing Risk

greene nh, easley rb

CONDENSED REVIEW OF PEDIATRIC ANESTHESIOLOGY, 2ND EDITION, EDITED BY CHRISTOPHER ESTRADA, STEPHEN STAYER, DAVID MANN, NICHOLAS CARLING, NIHAR PATEL, AND PAUL HOPKINS, 2014.

 

Conference Proceedings

Obstruction of Endotracheal Tube in an Infant with a Retropharyngeal and Anterior Mediastinal Abscess

thapa DB, greene NH, UDani AG

Medically challenging case, american society of anesthesiologists annual meeting, chicago, IL, october 24th, 2016

Airway management in a patient with Wolf-Hirschhorn Syndrome: A Case Report.

Gamble jf, kurian DJ, Greene nh

Medically challenging case, american society of anesthesiologists annual meeting, san diego, ca, October 24th, 2015

Cost-effectiveness of aprepitant for the prevention of postoperative nausea and vomiting

manning EL, habib as, greene nh

Scientific abstract, american society of anesthesiologists annual meeting, san diego, CA, october 26th, 2015

Estimation and Analysis of Unnecessarily Early Procedures in Infants Younger than Six Months of Age in the United States

Einhorn lm, Routh JC, Greene nh

Scientific abstract, american society of anesthesiologists annual meeting, san diego, ca, october 24th, 2015

Pediatric Sub-specialization and Inpatient Complication Rates for Pediatric Urology Procedures

tejwani R, Wang HS, Greene Nh, wolf s, wiener JS, routh JC

Scientific abstract, European society of Pediatric Urology/Society for Pediatric Urology Joint annual meeting, Prague, Czech Republic, October 14th ,2015

Diffusion Tensor Imaging of Corpus Callosum Microstructure After Neonatal Cardiac Surgery is Strongly Associated with 12-Month Neurodevelopmental Outcome Scores

Greene nh, Emerald AD, Easley RB, Brady KM, Hunter jv, wilde EA, Andropoulos DB

Scientific abstract, american society of anesthesiologists annual meeting, new orleans, LA, october 11th, 2014

Effects of Surgical Palliation and Perioperative Brain Injury on Corpus Callosum Microstructural Changes in the First Year of Life in Infants with Congenital Herat Disease

Greene NH, emerald AD, easley RB, brady KM, hunter JV, wilde Ea, andropoulos DB

Scientific abstract, society for pediatric anesthesia/congenital cardiac anesthesia society Annual meeting, fort lauderdale, March 6th-9th, 2014

Normalization of Fractional Anisotropy and Apparent Diffusion Coefficient Values Facilitate Appropriate Comparison of Corpus Callosum Microstructural Changes in the Developing Newborn.

Greene nh, emerald ad, easley rb, brady km, hunter jv, wilde ea, andropoulos DB

Scientific Abstract, society for pediatric anesthesia/congenital cardiac anesthesia society annual meeting, fort lauderdale, march 6th-9th, 2014

Variation in Pediatric Traumatic Brain Injury Outcomes in the United States

greene nh, kernic ma, vavilala ms, rivara fp

Scientific abstract, western anesthesia residents conference, albuquerque, NM, may 11th, 2013

The Perioperative Management of Carotid Endarterectomy Survey: Preliminary Findings

Greene NH, Minhaj MM, Zaky AF, rozet I

Scientific Abstract, New york state society of anesthesiologists 66th post graduate assembly, new york, NY, December 2012

Spinal anesthesia for Cesarean delivery in a woman with Neuromyelitis optica

Greene n, Dinges e, sedensky M, Landau R

Medically CHALLENGING case, American society of anesthesiologists annual meeting, Washington, DC, October 2012

CT Scan Measurement Predicts Loss of Resistance Depth During Thoracic Epidural Placement

Greene NH, Cobb BG, linnau KF, Kent CD

Scientific Abstract, American Society of anesthesiologists annual meeting, chicago, IL, October 15th-19th, 2011

There are no consistent definitions of hemodynamic aberrations in the anesthesia literature

Greene NH, Weldon BC, Monk TG

Scientific abstract, American society of anesthesiologists annual meeting, Orlando, FL, October 18th, 2008

Measures of Executive Function and Depression Predict Postoperative Delirium

Greene nh, attix dk, Macy SL, Monk TG

Scientific Abstract, American Society of Anesthesiologists annual meeting, orlando, FL, October 20th, 2008

Structural Basis for the Activation of Cholera Toxin by Human ARF6-GTP

GREENE NH, O'NEAL CJ, HOL WGJ

SCIENTIFIC ABSTRACT, HOWARD HUGHES MEDICAL INSTITUTE UNDERGRADUATE RESEARCH SYMPOSIUM, SEATTLE, WA, APRIL 20TH, 2005

Structure Based Drug Design Targeting Cholera Toxin

Greene NH, O'Neal CJ, Hol WGJ

Scientific ABSTRACT, mary gates annual undergraduate RESEARCH symposium, seattle, WA, may 14th, 2004

 

 

Research Awards

Mary Gates Undergraduate Research Scholar, 2003-2004

Howard Hughes Medical Institute Undergraduate Research Scholar, 2004-2005

Duke Roadmap Scholarship (NIH Funded Research Training Grant) - Clinical and Translational Science Award Scholarship TL1RR024126 - 2007

First Place Poster Award - Medical Student Category at Duke University Department of Anesthesiology Academic Evening - 2008

Best Abstracts of the Meeting - Top 10 Editor's Pick at National American Society of Anesthesiologists Annual Meeting - 2008

Best Abstracts, Honorable Mention - University of Washington Department of Anesthesiology Academic Evening - 2011

Foundation for Anesthesia Education and Research (FAER) Scholar - 2011

Judy Y.L. Su Endowed Research Training Award in Anesthesiology - University of Washington Department of Anesthesiology Academic Evening - 2013

Best Abstract in Category - Pediatric Anesthesia at Western Anesthesia Residents Conference - 2013

First Place/Top Poster - Basic Science/Clinical Research Poster Presentation at Western Anesthesia Residents Conference - 2013

Best Poster Award - Congenital Cardiac Anesthesia Society Annual Meeting - 2014

American Academy of Pediatrics John J. Downes Resident Research Award - Society of Pediatric Anesthesia Annual Meeting - 2014

 

Grant Support

Past:

Role: Lead Investigator
PI: Allison Ross, MD
Title: A Phase IIA, Open-label, Safety and Pharmacokinetic Study of Zorvolex Capsules in Pediatric Subjects 6 to <17 Years of Age with Mild to Moderate Acute Postoperative Pain Following Elective Surgery
Sponsor: Iroko Pharmaceuticals (Philadelphia, PA)
Amount: $169,000
Duration: 2015-2016

Present:

Role: Lead Investigator
PI: Allison Ross, MD
Title: An Open-Label Single-Dose and Randomized, Double-Blind, Placebo-Controlled Multiple-Dose Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Oxymorphone Hal for Acute Moderate to Severe Postoperative Pain in Pediatric Subjects"
Sponsor: Endo Pharmaceuticals (Dublin, Ireland)
Amount: $60,000
Duration: 2016-Present

Role: Principal Investigator
PI: Nathaniel Greene, MD, MHS, FAAP
Title: A Phase IIA, Open-label, Safety and Pharmacokinetic Study of Tivorbex capsules in Pediatric Subjects 6 to <17 Years of Age with Mild to Moderate Acute Pain Following Elective Surgery"
Sponsor: Iroko Pharmaceuticals (Philadelphia, PA)
Amount: $62,000
Salary Support: 5%
Duration: 2016-Present

Role: Lead Investigator
PI: Alex Kemper, Co-PI: Jennifer Li
Title: Surveillance of Congenital Heart Disease Across the Lifespan
Sponsor: Centers for Disease and Control (Atlanta, GA)
Amount: $1,800,000
Salary Support: 10%
Duration: 2016-Present

Role: Senior Investigator
PI: Warwick Ames
Title: A Study of Practice Behavior for Endotracheal Intubation Site for Children with Congenital Heart Disease Undergoing Surgery, Impact of Endotracheal Intubation Site on Perioperative Outcomes
Sponsor: Society of Thoracic Surgeons (Chicago, IL)
Amount: $25,000
Duration: 2016-Present
 

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Education


Education


Education

 

masters of health sciences in clinical research

Duke University Clinical Research Training Program, Durham, NC
2007-2008 and 2014-2015

 

Graduate Studies in Biostatistics and epidemiology

University of Washington School of Public Health, Seattle, WA, 2012-2013

 

Doctor of Medicine

Duke University School of Medicine, Durham, NC, 2005-2009

 

Bachelor of Sciences in Biochemistry with College Honors

University of Washington College of Arts and Sciences, Seattle, WA, 2002-2005

 

High School Diploma

James A. Garfield High School, Seattle, WA, 1998-2002

Nathaniel started his education in the Seattle Public School District and attended Sacajawea and Madrona Elementary School, Washington Middle School and James A. Garfield High School. Highlights of these years include receiving the Seymour Kaplan Humanitarian Award in 1995; representing the United States playing on an international basketball tour team in England, Ireland, Wales, and the Isle of Man; being named captain on his high school cross-country and track and field teams; and representing his high school on student council multiple years.

He was then proud to enroll at the University of Washington, where he worked his way into the Honors Program, became a resident advisor, and became heavily involved as an undergraduate in a structural biology research laboratory. Having earned college credits while in high school, he was able to graduate in three years and successfully apply to the Duke University School of Medicine, where he subsequently started medical school.

At Duke, he distinguished himself by earning the Duke Roadmap Scholarship, which funded a year of research with Terri Monk investigating postoperative cognitive dysfunction after surgery in older adults which ended up being very academically productive. Accomplishments during this year made him a great fit for a research track position at the University of Washington Anesthesiology Residency Program.

While in the research track at the University of Washington, he completed the core courses for a Masters of Public Health in Epidemiology and completed a thesis as well, and would have needed additional elective credits to finish the degree formally.

After accepting a faculty position at Duke University, he completed his coursework in the Duke Clinical Research Training Program (as well as another thesis), for which the first year was completed during his research year in medical school.

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Teaching


Teaching


Invited Lectures, Academic Teaching Topics, and Problem-Based Learning Discussions

Invited lectures

Clinical Studies and Risk Estimates

DUKE UNIVERSITY PEDIATRIC ANESTHESIA DIVISION CONFERENCE

DURHAM, NC - AUGUST 11TH, 2016

Twitter Journal Club - Does Midazolam Prevent Postoperative Nausea and Vomiting?

Duke University anesthesiology resident journal club (with Twitter discussion)

Durham, NC - May 12th, 2016

Pediatric Database Research: Opportunities to Lead, Limitations to Understand, and Powerful Answers to Disseminate

Grand Rounds, Duke university department of anesthesiology

durham, NC - February 10th, 2016

Obstructive Sleep Apnea in Pediatric Anesthesia - What's New in 2015

8th annual unc-duke-wake forest pediatric anesthesiology conference

Chapel hill, nc - September 13th, 2015

Ketorolac in Pediatric Surgical Patients - What's the Big Deal?

Duke university pediatric anesthesia division conference

Durham, NC - August 13th, 2015

Diffusion Tensor Imaging: A Unique Way to Image Microstructural Development in Neonates

duke pediatric cardiac intensive care weekly conference

durham, nc - february 15th, 2015

Intraoperative Emergencies

7th annual UNC-Duke-Wake Forest Pediatric Anesthesiology Conference

Chapel Hill, NC - September 6th, 2014

Journal Club - How to Appropriately Analyze Randomized Controlled Trials - A Case Study

Pediatric anesthesiology fellows' conference, texas children's hospital

houston, tX - May 27th, 2014

Normalization of Fractional Anisotropy and Apparent Diffusion Coefficient Values Facilitate Appropriate Comparison of Corpus Callosum Microstructural Changes in the Developing Newborn

best abstract session, society for pediatric anesthesia annual meeting

Fort lauderdale, FL - march 8th, 2014

Effects of Surgical Palliation and Perioperative Brain Injury on Corpus Callosum Microstructural Changes in the First Year of Life of Infants with Congenital Heart Disease

Best abstract session, congenital cardiac anesthesia society annual meeting

Fort Lauderdale, FL - March 6th, 2014

Pediatric Trauma and Burn Injury - Board Review

pediatric anesthesiology fellows' conference, texas children's hospital

houston, tx - january 24th, 2014

Journal Club - Assessing Perioperative Risk in Pediatric Patients with Heart Disease

Pediatric cardiovascular anesthesia conference, texas children's hospital

houston, tx - september 12th, 2013

Resident Research Track - Variation in Pediatric Traumatic Brain Injury Outcomes in the United States

Grand rounds, university of washington department of anesthesiology

seattle, wa - april 10th, 2013

Measures of Executive Function and Depression Identify Patients at Risk for Postoperative Delirium

top ten ABSTRACTS session, American society of anesthesiologists annual meeting

orlando, fl - october 20th, 2008


Academic teaching topics

Clinical Research Methodology, General Pediatric Anesthesia, Neurodevelopmental Effects of Anesthesia, Pediatric Trauma, Burns, and Resuscitation, Postoperative Pain Control in Pediatric Anesthesia, Epidemiology in Anesthesiology, National Variations in Clinical Outcomes


problem-based learning discussions (PBLDs)

Oh No! - My next case is a 15 year old who needs this operation, but he's DNR.

Greene NH, Mann DG

society for pediatric anesthesia spring annual meeting, march 8th, 2014

I don't have the faintest idea of what to do. A 9 year old with recurrent syncope presents with acute appendicitis.

Greene nh, Caplan LA

Society for pediatric anesthesia Fall annual meeting, october 10th, 2014

ENT can't intubate and you want to do a laparotomy in this preemie?

Pecorella SR, Greene nh

Society for pediatric anesthesia spring annual meeting, april 3rd, 2016

Single ventricle, scoliosis surgery, sans transfusion: Management of major surgery in a complex Jehovah's Witness teenager.

Einhorn lm, Greene nh

Society for pediatric anesthesia spring annual meeting, march 3rd, 2017

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Collaboration


Collaboration


Professional Memberships, National Collaborations, and Local Responsibilities

Professional memberships

American Medical Association - 2005 to present
American Society of Anesthesiologists - 2008 to present
International Anesthesiology Research Society - 2010 to present
Society for Pediatric Anesthesia - 2013 to present
Congenital Cardiac Anesthesia Society - 2013 to present
Society of Pediatric Pain Medicine - 2014 to present
American Academy of Pediatrics, Specialty Fellow - 2015 to present
Society of Thoracic Surgeons, Associate Member - 2015 to present


National Collaborations

Committee Member, Biomedical Informatics, Society for Pediatric Anesthesia
Committee Member, Research, Society for Pediatric Anesthesia
Committee Member, STS-CCAS Database, Society for Pediatric Anesthesia
Committee Member, Research, Society for Pediatric Pain Medicine

Liaison, Congenital Cardiac Anesthesia Society to STS-DCRI National Database Project Review Committee
Institutional Representative, Wake Up Safe National Quality Improvement Initiative
Member, Research and Communications, Wake Up Safe National Quality Improvement Initiative

PBLD Co-Chair, 2017 Annual Meeting Planning Committee, Society for Pediatric Anesthesia


Local RESPONSIBILITIES

Pediatric Anesthesia Fellowship Clinical Competency Committee, Member, 2014 - Present
Duke University Anesthesiology Residency Selection Committee, Interviewer, 2014 - Present
Duke University Pediatric Anesthesia Fellowship Core Faculty, Member, 2014 - Present
Duke University Anesthesiology DataMart Committee Member, Division Representative, 2014 - Present
Private Diagnostic Clinic Outcomes Research Team, Departmental Representative, 2015 - Present
Duke University Anesthesiology Simulation/Crisis Resource Management Instructor, 2015 - Present
Director, Anesthesia for Pediatric Scoliosis Surgery, 2015 - Present
Director, Research in Pediatric Anesthesia, 2015 - Present
Lead Consultant, Duke Perioperative Codonics Safe Label System Installation, 2016 - Present